There are
409 mi
from Omaha, NE to La Crosse, WI
That's the driving distance. It would take 7 hours 33 mins to go from Omaha, Nebraska to La Crosse, Wisconsin.
The flight distance (direct flight from Omaha, NE to La Crosse, WI) is 299.46 mi.
409 mi = 658.08 kms