There are
1,184 mi
from Omaha, NE to Cayce, SC
That's the driving distance. It would take 22 hours 8 mins to go from Omaha, Nebraska to Cayce, South Carolina.
The flight distance (direct flight from Omaha, NE to Cayce, SC) is 957.52 mi.
1,184 mi = 1.61 kms