There are
1,230 mi
from Odessa, TX to Sycamore, IL
That's the driving distance. It would take 22 hours 8 mins to go from Odessa, Texas to Sycamore, Illinois.
The flight distance (direct flight from Odessa, TX to Sycamore, IL) is 1,028.26 mi.
1,230 mi = 1.61 kms