There are
2,889 mi
from North Charleston, SC to Shasta Lake, CA
That's the driving distance. It would take 2 days 3 hours to go from North Charleston, South Carolina to Shasta Lake, California.
The flight distance (direct flight from North Charleston, SC to Shasta Lake, CA) is 2,383.93 mi.
2,889 mi = 4,649.75 kms