Miles between North Charleston, SC and Madisonville, KY

There are
648 mi
from North Charleston, SC to Madisonville, KY

That's the driving distance. It would take 12 hours 6 mins to go from North Charleston, South Carolina to Madisonville, Kentucky.

The flight distance (direct flight from North Charleston, SC to Madisonville, KY) is 525.51 mi.

648 mi = 1,042.84 kms