There are
2,611 mi
from North Charleston, SC to Lompoc, CA
That's the driving distance. It would take 1 day 22 hours to go from North Charleston, South Carolina to Lompoc, California.
The flight distance (direct flight from North Charleston, SC to Lompoc, CA) is 2,313.44 mi.
2,611 mi = 4,201.63 kms