There are
2,326 mi
from North Charleston, SC to Calexico, CA
That's the driving distance. It would take 1 day 16 hours to go from North Charleston, South Carolina to Calexico, California.
The flight distance (direct flight from North Charleston, SC to Calexico, CA) is 2,054.02 mi.
2,326 mi = 3,743.29 kms