There are
558 mi
from New Smyrna Beach, FL to Chapel Hill, NC
That's the driving distance. It would take 10 hours 43 mins to go from New Smyrna Beach, Florida to Chapel Hill, North Carolina.
The flight distance (direct flight from New Smyrna Beach, FL to Chapel Hill, NC) is 488.18 mi.
558 mi = 897.93 kms