There are
1,825 mi
from Murrieta, CA to St Charles, MO
That's the driving distance. It would take 1 day 7 hours to go from Murrieta, California to St Charles, Missouri.
The flight distance (direct flight from Murrieta, CA to St Charles, MO) is 1,526.69 mi.
1,825 mi = 1.61 kms