Miles between Mt Pleasant, SC and Middletown, OH

There are
642 mi
from Mt Pleasant, SC to Middletown, OH

That's the driving distance. It would take 12 hours 28 mins to go from Mt Pleasant, South Carolina to Middletown, Ohio.

The flight distance (direct flight from Mt Pleasant, SC to Middletown, OH) is 528.65 mi.

642 mi = 1,033.02 kms