There are
1,296 mi
from Missoula, MT to La Crosse, WI
That's the driving distance. It would take 22 hours 11 mins to go from Missoula, Montana to La Crosse, Wisconsin.
The flight distance (direct flight from Missoula, MT to La Crosse, WI) is 1,122.35 mi.
1,296 mi = 1.61 kms