There are
2,497 mi
from Missoula, MT to Gainesville, FL
That's the driving distance. It would take 1 day 20 hours to go from Missoula, Montana to Gainesville, Florida.
The flight distance (direct flight from Missoula, MT to Gainesville, FL) is 2,068.21 mi.
2,497 mi = 3.22 kms