There are
1,681 mi
from Missoula, MT to Desoto, TX
That's the driving distance. It would take 1 day 5 hours to go from Missoula, Montana to Desoto, Texas.
The flight distance (direct flight from Missoula, MT to Desoto, TX) is 1,337.25 mi.
1,681 mi = 1.61 kms