There are
977 mi
from Midland, TX to South Sioux City, NE
That's the driving distance. It would take 17 hours 32 mins to go from Midland, Texas to South Sioux City, Nebraska.
The flight distance (direct flight from Midland, TX to South Sioux City, NE) is 787.13 mi.
977 mi = 1,571.97 kms