There are
2,051 mi
from Middletown, OH to Twentynine Palms, CA
That's the driving distance. It would take 1 day 12 hours to go from Middletown, Ohio to Twentynine Palms, California.
The flight distance (direct flight from Middletown, OH to Twentynine Palms, CA) is 1,780.13 mi.
2,051 mi = 3,301.45 kms