There are
2,210 mi
from Middletown, OH to Thousand Oaks, CA
That's the driving distance. It would take 1 day 15 hours to go from Middletown, Ohio to Thousand Oaks, California.
The flight distance (direct flight from Middletown, OH to Thousand Oaks, CA) is 1,927.61 mi.
2,210 mi = 3,556.61 kms