There are
601 mi
from Middletown, OH to Shawnee, KS
That's the driving distance. It would take 11 hours 40 mins to go from Middletown, Ohio to Shawnee, Kansas.
The flight distance (direct flight from Middletown, OH to Shawnee, KS) is 552.60 mi.
601 mi = 966.70 kms