There are
2,374 mi
from Middletown, OH to San Ramon, CA
That's the driving distance. It would take 1 day 17 hours to go from Middletown, Ohio to San Ramon, California.
The flight distance (direct flight from Middletown, OH to San Ramon, CA) is 2,016.69 mi.
2,374 mi = 3,821.25 kms