There are
2,319 mi
from Middletown, OH to Lompoc, CA
That's the driving distance. It would take 1 day 17 hours to go from Middletown, Ohio to Lompoc, California.
The flight distance (direct flight from Middletown, OH to Lompoc, CA) is 2,002.46 mi.
2,319 mi = 3,732.40 kms