There are
605 mi
from Middletown, OH to Lenexa, KS
That's the driving distance. It would take 11 hours 45 mins to go from Middletown, Ohio to Lenexa, Kansas.
The flight distance (direct flight from Middletown, OH to Lenexa, KS) is 554.17 mi.
605 mi = 974.44 kms