There are
743 mi
from Middletown, OH to Fremont, NE
That's the driving distance. It would take 14 hours 8 mins to go from Middletown, Ohio to Fremont, Nebraska.
The flight distance (direct flight from Middletown, OH to Fremont, NE) is 649.04 mi.
743 mi = 1,195.42 kms