There are
1,080 mi
from Mesquite, TX to Thomasville, NC
That's the driving distance. It would take 19 hours 51 mins to go from Mesquite, Texas to Thomasville, North Carolina.
The flight distance (direct flight from Mesquite, TX to Thomasville, NC) is 965.47 mi.
1,080 mi = 1.61 kms