There are
2,056 mi
from Mesquite, TX to St Helens, OR
That's the driving distance. It would take 1 day 12 hours to go from Mesquite, Texas to St Helens, Oregon.
The flight distance (direct flight from Mesquite, TX to St Helens, OR) is 1,656.16 mi.
2,056 mi = 3.22 kms