Miles between Mesquite, TX and Sikeston, MO

There are
571 mi
from Mesquite, TX to Sikeston, MO

That's the driving distance. It would take 9 hours 54 mins to go from Mesquite, Texas to Sikeston, Missouri.

The flight distance (direct flight from Mesquite, TX to Sikeston, MO) is 488.43 mi.

571 mi = 919.46 kms