There are
674 mi
from Mesquite, TX to Shiloh, IL
That's the driving distance. It would take 12 hours 11 mins to go from Mesquite, Texas to Shiloh, Illinois.
The flight distance (direct flight from Mesquite, TX to Shiloh, IL) is 549.06 mi.
674 mi = 1,085.03 kms