There are
918 mi
from Mesquite, TX to Shelbyville, IN
That's the driving distance. It would take 16 hours 13 mins to go from Mesquite, Texas to Shelbyville, Indiana.
The flight distance (direct flight from Mesquite, TX to Shelbyville, IN) is 762.20 mi.
918 mi = 1,478.05 kms