There are
1,737 mi
from Mesquite, TX to San Bruno, CA
That's the driving distance. It would take 1 day 6 hours to go from Mesquite, Texas to San Bruno, California.
The flight distance (direct flight from Mesquite, TX to San Bruno, CA) is 1,490.47 mi.
1,737 mi = 2,794.64 kms