There are
1,436 mi
from Mesquite, TX to Salisbury, MD
That's the driving distance. It would take 1 day 2 hours to go from Mesquite, Texas to Salisbury, Maryland.
The flight distance (direct flight from Mesquite, TX to Salisbury, MD) is 1,238.70 mi.
1,436 mi = 1.61 kms