There are
1,005 mi
from Mesquite, TX to Piqua, OH
That's the driving distance. It would take 18 hours 7 mins to go from Mesquite, Texas to Piqua, Ohio.
The flight distance (direct flight from Mesquite, TX to Piqua, OH) is 853.85 mi.
1,005 mi = 1.61 kms