Miles between Mesquite, TX and Picayune, MS

There are
521 mi
from Mesquite, TX to Picayune, MS

That's the driving distance. It would take 9 hours 24 mins to go from Mesquite, Texas to Picayune, Mississippi.

The flight distance (direct flight from Mesquite, TX to Picayune, MS) is 435.36 mi.

521 mi = 838.27 kms