There are
224 mi
from Mesquite, TX to Okmulgee, OK
That's the driving distance. It would take 4 hours 5 mins to go from Mesquite, Texas to Okmulgee, Oklahoma.
The flight distance (direct flight from Mesquite, TX to Okmulgee, OK) is 200.72 mi.
224 mi = 359.99 kms