There are
1,966 mi
from Mesquite, TX to Medford, OR
That's the driving distance. It would take 1 day 12 hours to go from Mesquite, Texas to Medford, Oregon.
The flight distance (direct flight from Mesquite, TX to Medford, OR) is 1,575.23 mi.
1,966 mi = 1.61 kms