There are
1,157 mi
from Mesquite, TX to Mebane, NC
That's the driving distance. It would take 20 hours 49 mins to go from Mesquite, Texas to Mebane, North Carolina.
The flight distance (direct flight from Mesquite, TX to Mebane, NC) is 1,012.66 mi.
1,157 mi = 1,862.36 kms