There are
1,341 mi
from Mesquite, TX to Laurel, MD
That's the driving distance. It would take 1 day to go from Mesquite, Texas to Laurel, Maryland.
The flight distance (direct flight from Mesquite, TX to Laurel, MD) is 1,185.32 mi.
1,341 mi = 2,157.84 kms