There are
1,450 mi
from Mesquite, TX to Lansdowne, PA
That's the driving distance. It would take 1 day 2 hours to go from Mesquite, Texas to Lansdowne, Pennsylvania.
The flight distance (direct flight from Mesquite, TX to Lansdowne, PA) is 1,281.95 mi.
1,450 mi = 1.61 kms