There are
1,478 mi
from Mesquite, TX to Lansdale, PA
That's the driving distance. It would take 1 day 2 hours to go from Mesquite, Texas to Lansdale, Pennsylvania.
The flight distance (direct flight from Mesquite, TX to Lansdale, PA) is 1,287.29 mi.
1,478 mi = 1.61 kms