There are
876 mi
from Mesquite, TX to Kewanee, IL
That's the driving distance. It would take 16 hours 2 mins to go from Mesquite, Texas to Kewanee, Illinois.
The flight distance (direct flight from Mesquite, TX to Kewanee, IL) is 691.44 mi.
876 mi = 1,409.86 kms