There are
828 mi
from Mesquite, TX to Jeffersontown, KY
That's the driving distance. It would take 14 hours 44 mins to go from Mesquite, Texas to Jeffersontown, Kentucky.
The flight distance (direct flight from Mesquite, TX to Jeffersontown, KY) is 724.54 mi.
828 mi = 1,333.02 kms