There are
1,499 mi
from Mesquite, TX to Ithaca, NY
That's the driving distance. It would take 1 day 3 hours to go from Mesquite, Texas to Ithaca, New York.
The flight distance (direct flight from Mesquite, TX to Ithaca, NY) is 1,282.41 mi.
1,499 mi = 1.61 kms