There are
1,740 mi
from Mesquite, TX to Hillsborough, CA
That's the driving distance. It would take 1 day 7 hours to go from Mesquite, Texas to Hillsborough, California.
The flight distance (direct flight from Mesquite, TX to Hillsborough, CA) is 1,488.38 mi.
1,740 mi = 1.61 kms