There are
727 mi
from Mesquite, TX to Evansville, IN
That's the driving distance. It would take 12 hours 57 mins to go from Mesquite, Texas to Evansville, Indiana.
The flight distance (direct flight from Mesquite, TX to Evansville, IN) is 622.44 mi.
727 mi = 1,170.47 kms