There are
1,525 mi
from Mesquite, TX to Endicott, NY
That's the driving distance. It would take 1 day 4 hours to go from Mesquite, Texas to Endicott, New York.
The flight distance (direct flight from Mesquite, TX to Endicott, NY) is 1,293.85 mi.
1,525 mi = 2,454.79 kms