There are
845 mi
from Mesquite, TX to Danville, KY
That's the driving distance. It would take 15 hours 1 min to go from Mesquite, Texas to Danville, Kentucky.
The flight distance (direct flight from Mesquite, TX to Danville, KY) is 747.16 mi.
845 mi = 1,360.07 kms