There are
1,340 mi
from Mesa, AZ to Sioux City, IA
That's the driving distance. It would take 1 day 1 hour to go from Mesa, Arizona to Sioux City, Iowa.
The flight distance (direct flight from Mesa, AZ to Sioux City, IA) is 1,046.35 mi.
1,340 mi = 1.61 kms