Miles between Mesa, AZ and Port St Lucie, FL

There are
2,241 mi
from Mesa, AZ to Port St Lucie, FL

That's the driving distance. It would take 1 day 15 hours to go from Mesa, Arizona to Port St Lucie, Florida.

The flight distance (direct flight from Mesa, AZ to Port St Lucie, FL) is 1,916.37 mi.

2,241 mi = 3.22 kms