There are
1,874 mi
from Mesa, AZ to Chillicothe, OH
That's the driving distance. It would take 1 day 9 hours to go from Mesa, Arizona to Chillicothe, Ohio.
The flight distance (direct flight from Mesa, AZ to Chillicothe, OH) is 1,648.46 mi.
1,874 mi = 1.61 kms