There are
2,289 mi
from Medford, OR to Weslaco, TX
That's the driving distance. It would take 1 day 16 hours to go from Medford, Oregon to Weslaco, Texas.
The flight distance (direct flight from Medford, OR to Weslaco, TX) is 1,796 mi.
2,289 mi = 3,684.44 kms