There are
2,119 mi
from Medford, OR to Lufkin, TX
That's the driving distance. It would take 1 day 15 hours to go from Medford, Oregon to Lufkin, Texas.
The flight distance (direct flight from Medford, OR to Lufkin, TX) is 1,720.93 mi.
2,119 mi = 3,410.92 kms