There are
1,933 mi
from Medford, OR to Denison, TX
That's the driving distance. It would take 1 day 11 hours to go from Medford, Oregon to Denison, Texas.
The flight distance (direct flight from Medford, OR to Denison, TX) is 1,542.78 mi.
1,933 mi = 3,111.47 kms