There are
2,154 mi
from Medford, OR to Brenham, TX
That's the driving distance. It would take 1 day 14 hours to go from Medford, Oregon to Brenham, Texas.
The flight distance (direct flight from Medford, OR to Brenham, TX) is 1,687.49 mi.
2,154 mi = 3,465.97 kms